Interleukin-34 (IL-34) is a homodimeric cytokine identified by high throughput screening of human recombinant secreted factors. It contains no known conserved domains and has no sequence homology with other cytokines. IL-34 is recognized by colony-stimulating factor 1 receptor (CSF-1R). CSF-1R also binds CSF-1, also called macrophage colony-stimulating factor (M-CSF). Both IL-34 and CSF-1 are involved in the survival, proliferation, and differentiation of mononuclear phagocytes, including monocytes, macrophages, dendritic cells, Langerhans cells, microglia, and osteoclasts.
Mouse IL-34 Recombinant Protein
Interleukin-34 (IL-34) is a homodimeric cytokine recognized by colony-stimulating factor 1 receptor (CSF-1R). IL-34 is involved in the survival, proliferation, and differentiation of mononuclear phagocytes. Mouse IL-34 Recombinant Protein is purified interleukin-15 produced in yeast.
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The Mouse IL-34 protein can be used in cell culture, as an IL-34 ELISA Standard, and as a Western Blot Control.
• Protein Sequence: NENLEIWTLT QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL QKAHVSEREL RYLWVLVSLN ATESVMDVLL EGHPSWKYLQ EVQTLLENVQ RSLMDVEIGP HVEAVLSLLS TPGLSLKLVR PKALLDNCFR VMELLYCSCC KQSPILKWQD CELPRLHPHS PGSLMQCTAT NVYPLSRQTP TSLPGSPSSS HGSLP (215)
• Alias: Interleukin-34
• Source: yeast
• Molecular Weight: 24.6 kDa
• Form: Lyophilized
• Contains: Recombinant proteins produced in yeast
• Storage: -20°C
• Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping