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Mouse IL-18 Recombinant Protein

$180.00

Interleukin-18 (IL-18) is a proinflammatory cytokine that belongs to the IL-1 superfamily. IL-18 works together with IL-12 to induce cell-mediated immunity following infection, and IL-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. Mouse IL-18 Recombinant Protein is purified interleukin-18 produced in yeast.

Catalog # Product Size Quantity Price
6576 5 µg $180.00
Catalog #: 6576 Category:

Interleukin-18 (IL-18) is a proinflammatory cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily. IL-18 works together with IL-12 to induce cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-gamma (IFN-gamma) or type II interferon that plays an important role in activating macrophages or other cells.

Apart from its physiological role, interleukin-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. This proinflammatory cytokine can induce the IFN-gamma production of T cells, and the combination of this cytokine and IL-12 has been shown to inhibit IL-4 dependent IgE and IgG1 production and to enhance IgG2a production of B cells.

The Mouse IL-18 protein can be used in cell culture, as an IL-18 ELISA Standard, and as a Western Blot Control.

• Protein Sequence: NFGRLHCTTA VIRNINDQVL FVDKRQPVFE DMTDIDQSAS EPQTRLIIYM YKDSEVRGLA VTLSVKDSKM STLSCKNKII SFEEMDPPEN IDDIQSDLIF FQKRVPGHNK MEFESSLYEG HFLACQKEDD AFKLILKKKD ENGDKSVMFT LTNLHQS (157)
• Alias: Interleukin-18
• Source: yeast
• Molecular Weight: 18.1 kDa
• Form: Lyophilized
• Contains: Recombinant proteins produced in yeast
• Storage: -20°C
• Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping